The 4DCellFate network consists of+ Read more
11 European partner institutions (with 13 scientific laboratories), 2 SMEs, and a large pharma company
with scientific expertise in proteomics, structural biology, biochemistry, and cell biology tackling some of the most relevant questions of epigenetics and cell fate.
We started on 1.12.2011 and will run for 5 years.
The 4DCellFate movie
The project's main outputs are summarised in a 4DCellFate video that can be found on youtube. It includes interviews of the coordinator Luciano Di Croce and the two PIs Ernest Laue and Brian Hendrich as well as animations to explain the scientific background.
The 4DCellFate project aims to elucidate how the PRC and NuRD complexes control cell fate, by systematically analyzing various aspects of these complexes: their structure, their function in various cellular contexts, and their interactions with other regulatory factors, nucleic acids, and nucleosomes.
4DCellFate is a project in the 'Health Theme' of the European Commission's Seventh Framework Programme, with the grant agreement no. 277899.