Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation and in disease


Barcelona, February 13th, 2012. As life begins, embryonic stem cells start to divide and develop into tissue ("differentiate"). Each stem cell has the potential to differentiate into different types of tissue cells, such as neurons, muscle, or blood cells, and the molecular mechanisms that determine its fate are highly complex. The earliest steps of differentiation are orchestrated by sophisticated and dynamic protein machineries.

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