Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation and in disease

Ben Lehner awarded 2013 Eppendorf prize


Ben Lehner has been awarded the prestigious Eppendorf Award for Young European Investigators for 2013.

Ben was quick to point out that this award also directly reflects the top scientists he has working in his group.





The Lehner group at the CRG takes a systems biology approach to deciphering how—and most importantly, if—individual genome sequences can predict phenotypic fates. For instance, can knowing a person's genomic sequence allow them to predict their disease risk? (see also Lehner, Nat Rev Gen, 2013).


Obviously, one confounding issue is the epigenetic control of phenotype variation. Within the context of 4DCellFate, Ben's group is working towards integrating diverse, large-scale predictive networks into a model for PRC and NuRD functions. Creating predictive models for epigenetic regulatory pathways will greatly aid in the long-term goal of understanding genemic sequences at the individual level.


Ben's interview in Nature, about how he makes decisions for his career, is also fun to read.


Attached media: 
PDF icon 2013_Poster_Lehner.pdf781.44 KB