Structural & Functional Proteomics: Delving into Molecular Details 2013
The workshop “Structural and Functional Proteomics: Delving into Molecular Details” was held in Utrecht, 14-15 January, 2013.
This workshop was organized by Michiel Vermeulen and Frank Sobott, and was co-sponsored by 4DCellFate, the Cancer Genomics Centre (CGC), and Waters. The workshop took place in La Vie Utrecht (Lange Viestraat 351). It was open to the public, and no registration is required. Please find the program (with directions to reach the venue) attached below.
A mini-symposium with world-class researchers will highlight cutting-edge topics from the field of proteomics, such as the role of post-translational modifications on interaction proteomics. These talks are open to the public, and participants will have the chance tonetwork over coffee during the day or a drink afterward the talks.
A practical tutorial will be held specifically for 4DCellFate members on Tuesday afternoon. This interactive tutorial will deal with topics of interest, such as how to carry out the analysis of MS results. 4DCellFate members will also attend a dinner with the speakers on Monday evening, to promote networking within the consortium and with the speakers.
13:30 – 14:00 Registration
14:00 – 14:05 Frank Sobott: introduction
14:05 – 14:35 Albert Heck
Native mass spectrometry: a bridge between interactomics and structural biology
14:35 – 15:05 Kasper Rand
Analysis of protein conformation and interaccions by H/D exchange mass spectrometry (HDX-MS)
15:05 – 15:35 Frank Sobott
Ion mobility-MS for native proteins and complexes
15:35 – 16:05 Coffee break
16:05 – 16:35 Juri Rappsilber
Determining complex protein networks with residue-level resolution - science fiction or science reality?
16:35 – 17:05 Alex Leitner
An integrated workflow for chemical cross-linking/mass spectrometry: technology and applications
17:05 – 17:35 Henning Urlaub
Mass spectrometric investigations of protein-RNA interactions
17:35 – 19:00 Discussion/Beer session (open)
19:30 – 22:00 Dinner with speakers (4DCellFate only)
9:00 – 9:05 Michiel Vermeulen: introduction
9:05 – 9:35 Anne-Claude Gavin
Systematic screens for protein–lipid interactions in Saccharomyces cerevisiae
9:35 – 10:05 Tiziana Bonaldi
The regulatory potential of protein methylation in gene expression investigated by MS-based proteomics
10:05 – 10:35 Coffee break
10:35 – 11:05 Jesper Olsen
Global proteomic analysis of PTMs in tissue samples
11:05 – 11:35 Matthias Selbach
11:35 – 12:05 Michiel Vermeulen
Quantitative proteomics reveals dynamic readers for 5-(hydroxy)methylcytosine during development
12:15 – 14:00 Lunch buffet
14:00 – 17:00 Workshop (4DCellFate only)